The question we address in this talk is whether one can formulate a theory-based equation, perhaps akin to that used for electron transfer reactions, for interpreting experiments and computations, to “unify” the diverse field. Authors have recognized that the transfer of light particles, such as protons from one reactant to another, common to enzymatic reactions, has some similarity to the transfer of an electron from one reactant to another. A simple theoretical equation for electron transfer reactions served to coordinate a vast body of experimental data and later provided guidance and insight into subsequent computations. In this lecture, we consider the similarity and differences of H–, H+ and H• transfers compared to electron transfers and formulate an approximate theoretical expression. Comparison can be made with experimental and computational results to explore its usefulness as a “unifier” of current results.