The Path to Invention and Discovery in Catalysis

Sir David W.C. MacMillan

Category: Lectures

Date: 26 June 2022

Quality: HD MD SD

The Path to Invention and Discovery in Catalysis (2022) - Sir David W.C. MacMillan

Abstract

This lecture will first describe the advent of organocatalysis in my laboratory. As part of this overview, we will highlight why organic catalysts have become widely explored in modern synthetic chemistry. We will next discuss how organocatalysis created a bridge to the development of a new field of research in my laboratory: visible-light photoredox catalysis involving copper. In this context, we will explore why a healthy balance of reaction discovery and mechanistic understanding has been important to the development of photocatalysis, which is now being widely adopted in both industrial and academic settings. Finally, we will examine an exciting recent application of photoredox catalysis in my group; namely, the high-resolution µMap technology, which provides a powerful means to probe biological pathways at the subcellular level.